Modulation of gamma oscillations in the pedunculopontine nucleus ( PPN ) by 1 neuronal calcium sensor protein - 1 ( NCS - 1 ) : 2 Relevance to schizophrenia and bipolar disorder 3 4
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چکیده
Modulation of gamma oscillations in the pedunculopontine nucleus (PPN) by 1 neuronal calcium sensor protein-1 (NCS-1): 2 Relevance to schizophrenia and bipolar disorder 3 4 Stasia D’Onofrio, Nebojsa Kezunovic, James R. Hyde, Brennon Luster, 5 Erick Messias, Francisco J. Urbano, and Edgar Garcia-Rill 6 Center for Translational Neuroscience, 7 Departments of Neurobiology and Developmental Sciences and Psychiatry, 8 University of Arkansas for Medical Sciences, 9 Little Rock, AR, USA, and 10 IFIBYNE-CONICET-UBA, Argentina. 11 * Authors contributed equally as last authors. 12 13 14 Abbreviated Title: Modulation of PPN gamma by NCS-1 15 16 Corresponding author: E. Garcia-Rill, PhD, 17 Director, Center for Translational Neuroscience 18 Department of Neurobiology and Developmental Sciences, 19 University of Arkansas for Medical Sciences, Slot 847 20 4301 West Markham St. 21 Little Rock, AR 72205 22 TEL. 501-686-5167; FAX. 501-526-7928 23 [email protected] 24 25 26 Articles in PresS. J Neurophysiol (November 5, 2014). doi:10.1152/jn.00828.2014
منابع مشابه
Modulation of gamma oscillations in the pedunculopontine nucleus by neuronal calcium sensor protein-1: relevance to schizophrenia and bipolar disorder.
Reduced levels of gamma-band activity are present in schizophrenia and bipolar disorder patients. In the same disorders, increased neuronal calcium sensor protein-1 (NCS-1) expression was reported in a series of postmortem studies. These disorders are also characterized by sleep dysregulation, suggesting a role for the reticular activating system (RAS). The discovery of gamma-band activity in t...
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